Fundamentals of Biofabrication

Fundamentals of Biofabrication

Delivery institution

Faculty of Medicine
Department of Orthopaedics

Instructor(s):

Paulina Nunez Bernal

Start date

17 November 2025

End date

1 February 2026

Study field

CHARM priority field

Study level

Study load, ECTS

3

Short description

Biofabrication combines advanced 3D fabrication techniques with biological systems to create
complex tissue constructs, which can be applied for tissue engineering, as 3D in vitro biological
models, or as medical therapeutic products. This online course aims to provide the student with
the fundamental knowledge on the various aspects of biofabrication, including 3D printing
techniques, biomaterials, tissue engineering, applications, translation and ethics.

Full description

https://osiris.uu.nl/osiris_student_uuprd/OnderwijsCatalogusSelect.do?
selectie=cursus&cursus=BMB502816&collegejaar=2018&taal=en

Learning outcomes

Understand and apply knowledge of biofabrication, ecompassing 3D printing techniques,
biomaterial science, and tissue engineering: Able to describe different 3D printing techniques and
biomaterials used in biofabrication, as well as different applications Able to process medical
imaging data into printable CAD models Able to describe the role of (stem) cells in the
development of specialised tissues and appreciate the rationale for regenerative medicine
strategies Able to describe the cell-matrix interactions and the mechanical properties of specialised
tissues Able to describe the interaction of implanted cells and biomaterials in living organisms
Able to describe and distinguish different in vitro, in vivo and ex vivo research models and
techniques, and determine which models/techniques are appropriate for answering a specific
research/clinical question Able to describe techniques for the in vitro manipulation of cells and
biomaterials to engineer tissues for regenerative medicine purposes or in vitro models Able to
describe which challenges and approaches dominate the frontier research in biofabrication and/or
regeneration of various tissues Able to discuss ethical aspects of tissue engineering Critically
evaluate scientific literature Function effectively in multidisciplinary, international (study) groups.

Course requirements

Motivation letter detailing reasons for participating in the course + interest in the subject area of biofabrication

Places available

5

Course literature (compulsory or recommended):

Recommended literature list provided at the start of the course

Planned educational activities and teaching methods:

Recorded lectures, reading exercises, quizzes, group and individual assignments

Course code

BMB502816

Language

Assessment method

40% written assignment, 40% participation, 20% individual weekly assignments

Final certification

Transcript of records

Assessment date

1 February 2026

Modality

Learning management System in use

Brightspace

Contact hours per week for the student:

10

Specific regular weekly teaching day/time

Time zone